What is Leaky Gut / Gut Permeability?
Leaky gut, also known as increased intestinal permeability, occurs when the lining of the small intestine becomes damaged or inflamed, allowing substances such as toxins, microbes, and partially digested food particles to pass into the bloodstream. This disruption may trigger inflammation and contribute to a range of digestive and systemic symptoms. Although research is ongoing, leaky gut is increasingly recognised as a potential factor in chronic gastrointestinal and immune-related conditions.
What are the Causes of Leaky Gut / Gut Permeability?
Leaky gut can develop when factors weaken the gut barrier or disrupt the balance of gut bacteria. Common causes include:
- Poor diet: High sugar, processed foods, and low fibre intake may damage the intestinal lining.
- Chronic stress: Prolonged stress can alter immune function and increase inflammation.
- Infections: Bacterial, viral, or fungal infections can impair gut integrity.
- Medications: Non-steroidal anti-inflammatories, antibiotics, and alcohol may increase permeability.
- Underlying conditions: Coeliac disease, Crohn’s disease, and IBS are associated with gut barrier dysfunction.
What are the Symptoms of Leaky Gut / Gut Permeability?
Symptoms vary from digestive discomfort to systemic complaints and may include:
- Digestive issues: Bloating, diarrhoea, constipation, and abdominal pain.
- Food sensitivities: Reactions to gluten, dairy, or other common foods.
- Skin problems: Eczema, acne, or rashes linked to inflammation.
- Fatigue and brain fog: Possible result of immune activation and nutrient malabsorption.
How is Leaky Gut / Gut Permeability Diagnosed?
There is no single definitive test, but diagnosis may involve symptom assessment, medical history, and laboratory tests such as stool analysis, blood markers, or specialised permeability testing. Evaluation for underlying inflammatory or autoimmune conditions may also be done.
What are the Treatment Options for Leaky Gut / Gut Permeability?
Treatment focuses on reducing inflammation, supporting gut healing, and managing underlying factors. Strategies can include dietary changes (high fibre, reduced processed foods), probiotics, targeted supplements, stress management, and treatment of associated conditions. Persistent or severe cases may benefit from specialist referral and personalised nutritional support.