What is the Gut Microbiome?
Your gut is your gastrointestinal (GI) system or digestive system and includes your stomach, small intestine, and large intestine (colon). It digests and absorbs nutrients from food and utilizes those nutrients to fuel and maintain your body.
About 1000 different species of bacteria, viruses, and fungi reside in your colon. The bacteria and other microorganisms in your gut are known as your gut microbiome. The bacteria help to break down food, converting it into nutrients your body can utilize.
Certain types of microorganisms in your gut may be harmful to your health, but many are beneficial and necessary for a healthy body. In the gut microbiome, the "good" bacteria do more than just help with digestion. They help keep your "bad" bacteria under control. They multiply from time to time to devoid the unhealthy bacteria of space from growing.
Fiber-rich foods, for instance, are crucial for fiber-eating bacteria that are linked with a healthy gut microbiome. On the other hand, ultra-processed foods can encourage harmful bacteria to grow and upset the gut's delicate balance. A healthy balance of bacteria in your gut is vital to achieve equilibrium and optimal gut health.
How Can the Gut Microbiome Affect Your Health?
- Weight loss and gut microbiome: A balanced gut microbiome is not just about digestion; it plays a significant role in fitness and weight management. For athletes, a healthy gut can reduce gastrointestinal problems like bloating, enhance nutrient absorption, and improve recovery by reducing inflammation and fatigue after workouts. The process by which gut bacteria ferment fiber-rich foods and produce short-chain fatty acids (SCFAs) like butyrate is key here, as these molecules help improve muscle energy availability and recovery.
- Diabetes and gut microbiome: The role of the gut microbiome in regulating insulin and blood sugar levels is profound. Type 2 diabetes, characterized by high blood sugar levels due to insulin resistance, has been linked to microbial imbalances in the gut. Some bacteria can enhance insulin sensitivity, while others might contribute to increased insulin resistance, demonstrating the microbiome's critical role in diabetes management.
- Fatty Liver and gut microbiome: Gut bacteria also influence liver health, particularly in how they metabolize different nutrients and affect fat storage within the liver. This is evident in conditions like non-alcoholic and alcoholic fatty liver diseases, where an imbalance in gut microbiome can lead to increased fat accumulation and liver inflammation.
- Gut microbiome in Crohns and Ulcerative colitis: Inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, are significantly influenced by the gut microbiome. An imbalance, or dysbiosis, in gut bacteria can lead to these conditions. For example, a decrease in beneficial bacteria like Faecalibacterium prausnitzii, known for its anti-inflammatory properties, can trigger or worsen the inflammatory processes in these diseases.
- Gut Microbiome and Longevity: In the quest for a longer, healthier life, optimizing your gut health plays a crucial role. The gut microbiome directly impacts not only your digestive well-being but also your overall longevity. By focusing on improving your gut microbiome, you can significantly enhance your quality of life as you age, promoting a healthy lifestyle that supports living longer.
What tests can help you understand your gut microbiome?
Gut Microbiome Test
Gut microbiome tests are tests employed to evaluate the level of microorganisms in your GI tract. These tests can provide an idea of the types and amounts of microorganisms in your gut. Gut microbiome tests commonly use stool samples to examine gut flora and measure gut health.
Dr. Gyawali uses the latest DNA technology called shotgun metagenomics sequencing technique to analyse the gut microbiome. This provides the most detailed information and also allows extrapolation of the amount helpful or harmful substances the gut microbiome is producing. Metabolites such as butyrate, indoleproprionic acid and hexapolysacharides can be assessed.
Dr. Gyawali will use the results of the gut microbiome test to individualize any recommendation taking into account the reason for you undertaking the test.